Immunological aspects of COVID-19: what we know so far
نویسندگان
چکیده
The newly emerged severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the disease that it causes 2019 (COVID19) have changed world. Many virulence factors immune mechanisms contribute to deteriorating effects during SARS-CoV-2 infection. Both humoral cellular responses are involved in pathophysiology of disease. clinical picture COVID-19, memory reinfection remains unclear unpredictable. An electronic search PubMed, Cochrane Library Google scholar was performed, citation relevance determined according aim review.Other relevant literature manually searched as compliment. More than 60 scientific articles reports were considered. We reviewed describing immunological aspects COVID-19.Through this review, we tried explain theimmune pathogenesis SARS CoV 2infection providing high-quality evidence understand pathophysiology, its interaction with target cells response virus, including contribution dysfunctional progression patients based on recent research progress knowledge from researches MERS CoV. Different therapeutic options been implemented find effective, even though not specific, treatment disease, many hopes put developing an effective vaccine against virus. Understanding immunopathogenesis COVID-19 may provide important clues for treatments disease.
 Bangladesh J Medicine January 2021; 32(1) : 43-52
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ژورنال
عنوان ژورنال: Bangladesh Journal of Medicine
سال: 2021
ISSN: ['1023-1986', '2408-8366']
DOI: https://doi.org/10.3329/bjm.v32i1.51094